Brandoch Cook brc2018@med.cornell.edu Department of Surgery Weill Cornell Medical College 1300 York Avenue Rm LC-711 New York, NY, 10065 phone (212) 746-9485 / fax (212) 746-7378

Research

My projects in the laboratory primarily involve the creation of loss-of-function models in mouse embryonic stem cells and zebrafish using conditional transgenic expression of interfering RNA hairpins. I am currently using these systems to examine the role of BMP effector molecules, particularly the SMAD family of transcription factors, in primitive and definitive hematopoeisis.

Education

PhD	Sackler Institute of Biomedical Sciences	2008
MS	Sackler Institute of Biomedical Sciences	2002
BA	University of Colorado	1996

Publications

Ferrari G, Cook BD, Terushkin V, Pintucci G, Mignatti P. Transforming growth factor-beta 1 (TGF-beta1) induces angiogenesis through vascular endothelial growth factor (VEGF)-mediated apoptosis. J Cell Physiol. 2009 May;219(2):449-58.

Cook BD, Ferrari G, Pintucci G, Mignatti P. TGF-beta1 induces rearrangement of FLK-1-VE-cadherin-beta-catenin complex at the adherens junction through VEGF-mediated signaling. J Cell Biochem. 2008 Dec 15;105(6):1367-73.

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